Figure 2From: T-cell epitope prediction and immune complex simulation using molecular dynamics: state of the art and persisting challengesthe escalating scale necessary to simulate large-scale immunological phenomenon. (A) Model of the MHC alone, equivalent in size to the simulation undertaken in [150]. (B) Model of the MHC complexed to the TCR, equivalent in size to the simulations undertaken in [151]. (C) Complete model of a unit of the immune synapse, comprising MHC, TCR, peptide, CD4, and two opposing sections of membrane, as simulated in [141].Back to article page