Skip to main content

Table 4 Experimental conditions and associated information archived in AntiJen. Number of recorded experimental conditions stored within the AntiJen database. For each condition (temperature, pH, etc.) we show here the number of entries within a particular sub-database. [Standard] is the concentration of labelled standard peptide in an assay. Likewise, [competitor] is the concentration of competitor peptide within a competition assay. [peptide] is the concentration of peptide in a kinetic experiment. The Method category refers to a standard procedure used to perform a particular assay. Differences in the number of recorded data, relative to figures in Table 1, arise primarily from the omission of key details from particular papers. Archiving of experimental conditions is on-going.

From: AntiJen: a quantitative immunology database integrating functional, thermodynamic, kinetic, biophysical, and cellular data

DATABASE

TOTAL

pH

Temperature

[standard]

Stand. peptide seq.

[competitor]

Method

[peptide]

MHC Binding

15454

6679

9831

10893

12796

5007

1251

 

MHC Kinetics

1150

677

1101

   

1149

606

TAP Binding

1106

22

243

1092

1101

86

981

 

TCR-pMHC

782

426

632

   

668

 

IPPI a

2675

726

1371

   

2600

 

Copy Number

414

183

278

   

414

 

Peptide Libraries

897

 

897

   

897

 

Diffusion Coefficient

759

321

668

   

736

 

Antibody

395

119

115

   

372

Â