PREDTAP: a system for prediction of peptide binding to the human transporter associated with antigen processing

Immunome Research

Table 5 Amino acid position of top 5% predicted TAP binders in Human papillomavirus type 16 E6 (P03126) by SVMTAP, TAPPred and PRED^TAP. The positions marked by "+" were selected by four prediction models. The positions marked by ""were selected by three prediction models. The experimentally identified HLA-A0301 binders are ¹7–15, ²33–41, ³42–50, ⁴59–67, ⁵75–83, ⁶89–97, ⁷93–101, and ⁸125–133). The predictions in the table marked by ^1–8 are within 16-mers containing respective HLA-A*0301 binders

SVMTAP	TAPPred (SVM)	TAPPred (Cascade SVM)	PRED^TAP (ANN)	PRED^TAP (HMM)
75^5,+	53^4,+	5¹	75^5,+	75^5,+
131⁸	68	60⁴	53^4,+	46^3,*
53^4,+	80⁵	49³	46^3,*	61⁴
150	81⁵	132⁸	68	47³
130⁸	75^5,+	93⁷	83	7¹
46^3,*	131⁸	116	59⁴	53^4,+
134	134	67	42³	49³
146	51	40^2,3	130⁸	83⁶