Figure 4

Candidate binding sites. Candidate residues involved in antibody-antigen (RV6-26-VP6) binding as predicted from the three best computational docking refinements. The antibodies for the three complexes are hidden except for the tyrosines (red), which act as probes for detecting candidate viral residues for mutagenesis (green). VP6 side chains (all in the same monomer) that are within 5Å of a tyrosine probe are shown in green.