Immunome Research

Table 3 Specificity factors derived from positional scanning combinatorial library matrices identify primary anchor positions.

From: Quantitative peptide binding motifs for 19 human and mouse MHC class I molecules derived using positional scanning combinatorial peptide libraries

		SF¹
System	Allele	P1	P2	P3	P4	P5	P6	P7	P8	P9
HLA	A*0201	2.28	10.36	0.61	0.28	0.49	0.35	0.35	0.43	9.42
	A*3001	1.41	0.72	7.54	0.27	0.52	0.65	0.96	0.45	3.31
	A*3201	0.89	2.85	0.57	0.64	0.81	0.44	1.06	0.50	5.69
	A*6802	1.32	4.59	1.13	0.62	0.48	0.38	0.41	0.84	3.75
	B*0702	0.59	13.70	1.43	0.48	0.42	0.40	0.30	1.16	3.06
	B*0801	0.85	1.05	1.10	0.31	2.53	2.78	0.35	0.54	2.44
	B*1501	0.70	2.11	0.72	0.53	0.37	0.71	0.49	1.07	12.95
	B*1503	0.73	3.22	0.92	0.34	0.48	0.43	1.08	0.74	8.17
	B*2705	0.77	36.73	0.77	0.50	0.85	0.79	0.41	0.39	0.83
	B*3501	0.94	3.55	0.75	0.86	0.41	0.61	0.54	0.71	4.79
	B*5101	1.34	2.57	0.59	0.29	0.46	0.59	0.37	0.44	39.03
	B*5301	2.07	3.68	1.29	0.41	0.59	0.36	0.57	0.36	5.80
	B*5401	1.02	9.12	2.21	0.28	0.32	0.32	0.31	0.67	8.30
	B*5801	0.81	4.49	0.71	0.43	0.68	0.45	1.02	0.64	4.54
	B*5802	1.47	1.79	0.74	0.37	0.57	0.57	2.08	0.50	4.10
H-2	Db	1.18	1.07	1.39	0.35	3.61	0.28	0.42	0.79	4.93
	Dd	0.37	3.24	17.14	0.21	0.59	0.22	2.29	0.20	3.89
	Kd	0.31	52.55	0.61	0.51	0.73	0.38	0.75	0.23	4.14
	Kk	0.36	8.69	0.56	0.35	1.06	0.32	1.20	0.49	8.13

1. SF > 2.4, identifying primary anchor positions, are highlighted by bold font.

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