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Figure 2 | Immunome Research

Figure 2

From: Peptide length significantly influences in vitro affinity for MHC class II molecules

Figure 2

Regression plot of classes of peptide length additions. Five regression lines relating observed differences in affinity to final peptide length for each magnitude of peptide elongation. The content of this figure shows two important points relating sequence length and MHC class II affinity. Firstly, when correcting for final peptide length a greater length addition will generate a greater increase in affinity e.g. for peptides with a final length of 14 amino acids increasing the length by four residues has a much greater effect than a single residue increase. Secondly, from the included data it is possible to observe a length of between 18 and 20 amino acids, beyond which, increasing the length of the peptide has a null or negative effect.

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