Figure 3

Presence or absence of specific Toll-like receptor (TLR) 3 pathway elements in different cell types according to the currently available knowledge. (A) Section of TLR3 pathway described in DCs; (B) Section described in macrophages. Grey elements are members of the pathway whose presence has not been demonstrated in the specific cell type (DCs and macrophages, respectively). Blue elements and lines indicate reactions and entities that depend on absent (grey) members and thus may not occur. The complete pathway representations are available as Additional file 3 Figure Sl and Additional file 4 Figure S2.