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Table 3 MHC binding affinity assay for peptides that were identified with predictive algorithms for HLA-A03 supertype

From: Human immunome, bioinformatic analyses using HLA supermotifs and the parasite genome, binding assays, studies of human T cell responses, and immunization of HLA-A*1101 transgenic mice including novel adjuvants provide a foundation for HLA-A03 restricted CD8+T cell epitope based, adjuvanted vaccine protective against Toxoplasma gondii

    

HLA-A03-SUPERTYPE

 

PEPTIDE SEQUENCE

LENGTH

PROTEIN

POSITION

HLA-A*0301

HLA-A*1101

HLA-A*3001

HLA-A*3101

HLA-A*3301

HLA-A*6801

SUPERTYPE ALLELES BOUND

STFWPCLLR

9

SAG2C

13-21

22

10

1272

1.2

3.4

0.97

5

SSAYVFSVK

9

SPA

250-258

12

10

1826

97

181

2.1

5

AVVSLLRLLK

10

SPA

89-98

17

34

8.1

1296

1100

94

4