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Figure 4 | Immunome Research

Figure 4

From: Factors important in evolutionary shaping of immunoglobulin gene loci

Figure 4

Gene locus properties as function of the mutation rates. Shown are the effects of segment duplication (A-D), segment deletion (E-H) and point mutation (I-L) rates on the average genome size (A, E, I), the average fitness (B, F), the average number of families in a genome of an organism (where strings which have more than 80% similarity belong to the same family; C, G, K) and the average inter-mixing of the families in the genome (D, H, L). Varying the point mutation rate generated no meaningful changes in the fitness (not shown). The average family size - which is the genome size divided by the family number - is shown as function of the point mutation rate (J) to illustrate the rapid drop in the family size as the mutation rate increases. The size of the genome is increase drastically as a function of the segment duplication rate, and so does the mixing of the families (note the different scales).

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