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Figure 9 | Immunome Research

Figure 9

From: An integrated approach to epitope analysis I: Dimensional reduction, visualization and prediction of MHC binding using amino acid principal components and regression approaches

Figure 9

Example of visualization of physicochemical interactions between the peptide and the binding pocket of DRB3*0101. Potential effects of physicochemical interactions on the binding affinity can be explored interactively for all combinations of peptide amino acid and binding groove domain. (A) Inter-relationship of principal property 1 (hydrophobicity) for positions P9 and P(C+1). (B) rotation of the hyperplane of (A) to show the scatter of the residuals of the fit about this hyperplane.

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Immunome Research

ISSN: 1745-7580