Table 3 Vaxign-predicted vaccine targets from B. abortus strain 2308.
From: Bioinformatics analysis of Brucellavaccines and vaccine targets using VIOLIN
# | Locus Tag | RefSeq # | Symbol | TMH | Adhesin Prob. | Con-ed | Host Simil. | Protein Notes |
|---|---|---|---|---|---|---|---|---|
Cell Motility | ||||||||
1 | BAB2_1097 | YP_419224.1 | FlgK | 0 | 0.535 | X | Â | flagellar hook-associated protein FlgK |
2 | BAB2_1098 | YP_419225.1 | FlgE | 0 | 0.749 | X | Â | flagellar hook protein FlgE |
3 | BAB1_0260 | YP_413736.2 | FlgJ | 0 | 0.656 | Â | Â | Flagellar protein FlgJ:Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase |
4 | BAB1_1726 | YP_415076.1 | Â | 1 | 0.229 | X | Â | hypothetical protein |
TonB-dependent Receptor Protein: Inorganic Ion Transport and Metabolism | ||||||||
5 | BAB2_0233 | YP_418452.1 | Â | 0 | 0.405 | X | Â | TonB-dependent receptor protein |
6 | BAB2_1150 | YP_419272.1 | Â | 0 | 0.691 | X | Â | TonB-dependent receptor protein:Pollen allergen Poa pIX/Phl pVI, C-terminal |
7 | BAB1_1367 | YP_414742.1 | Â | 0 | 0.655 | X | Â | TonB-dependent receptor protein |
ATP/GTP-binding Site Motif A (P-loop): Porin, Alpha proteobacteria type | ||||||||
8 | BAB1_0659 | YP_414101.1 | Omp2a | 0 | 0.611 | Â | Â | Porin, alpha proteobacteria type |
9 | BAB1_0660 | YP_414102.1 | Omp2b | 0 | 0.585 | X | Â | Porin, alpha proteobacteria type |
Cell wall/membrane/envelope Biogenesis | ||||||||
10 | BAB1_0045 | YP_413545.1 | Â | 0 | 0.388 | X | Â | Bacterial surface antigen (D15) |
11 | BAB1_0115 | YP_413611.1 | Â | 0 | 0.793 | X | Â | outer membrane protein, putative |
12 | BAB1_0116 | YP_413612.1 | Â | 0 | 0.58 | X | Â | outer membrane protein, putative |
13 | BAB1_0707 | YP_414149.1 | Â | 0 | 0.635 | X | Â | Organic solvent tolerance protein |
14 | BAB1_0722 | YP_414164.1 | Omp25 | 0 | 0.554 | X | Â | OmpA-like transmembrane domain |
15 | BAB1_1176 | YP_414567.1 | Â | 1 | 0.408 | X | Â | Bacterial surface antigen (D15) |
16 | BAB1_1226 | YP_414612.1 | Â | 3 | 0.571 | X | Â | MotY protein: OmpA/MotB domain |
17 | BAB1_1302 | YP_414685.1 | RopB | 1 | 0.815 | X | Â | hypothetical protein |
18 | BAB1_1579 | YP_414943.1 | Â | 1 | 0.669 | X | Â | OmpW family |
19 | BAB1_1639 | YP_414995.1 | Omp31-1 | 0 | 0.736 | X | Â | OmpA-like transmembrane domain |
20 | BAB1_1707 | YP_415057.1 | Â | 0 | 0.371 | X | Â | MotY protein: OmpA/MotB domain |
21 | BAB2_0314 | YP_418525.1 | Â | 1 | 0.649 | X | Â | heat resistant agglutinin 1 precursor |
22 | BAB1_0963 | YP_414386.1 | Â | 0 | 0.415 | X | Â | Outer membrane efflux protein |
Replication, Recombination and Repair | ||||||||
23 | BAB2_0636 | YP_418811.1 | Â | 0 | 0.299 | X | Â | DNA topoisomerase I |
24 | BAB1_0121 | YP_413617.1 | Â | 0 | 0.162 | X | X | DEAD/DEAH box helicase |
Lipid Transport and Metabolism | ||||||||
25 | BAB1_0967 | YP_414390.1 | Â | 0 | 0.764 | Â | Â | Membrane protein involved in aromatic hydrocarbon degradation |
Posttranslational Modification, Protein Turnover, Chaperones | ||||||||
26 | BAB1_1944 | YP_415281.1 | Â | 1 | 0.518 | X | Â | PpiC-type peptidyl-prolyl cis-trans isomerase |
Unknown Function | ||||||||
27 | BAB1_1705 | YP_415055.1 | Â | 0 | 0.594 | X | Â | TPR repeat:Molluscan rhodopsin C-terminal tail |
28 | BAB1_1854 | YP_415198.1 | Â | 0 | 0.759 | Â | Â | hypothetical protein |
29 | BAB2_0071 | YP_418316.1 | Â | 0 | 0.492 | X | Â | hypothetical protein |
30 | BAB1_0069 | YP_413569.1 | Â | 0 | 0.886 | Â | Â | hypothetical protein BAB1_0069 |
31 | BAB1_0897 | YP_414322.1 | Â | 2 | 0.279 | X | Â | Antifreeze protein, type I |
32 | BAB1_0942 | YP_414367.1 | Â | 1 | 0.346 | X | Â | RNA-binding region RNP-1 (RNA recognition motif) |