State of the art and challenges in sequence based T-cell epitope prediction

Immunome Research

Table 1 Performance of available pan-specific predictors.

Performance Measure	Kiss	ADT	NetMHC	NetMHCpan
Pearson CC	0.455	0.488	0.593	0.620
Spearmans Rank CC	0.44	0.522	0.561	0.600
AUC	0.734	0.756	0.807	0.820

Performance values taken from [74]. The prediction servers have been evaluated on a set of binders to 17 HLA-A alleles and 16 HLA-B alleles. The data had not been used for training of any of the tested alleles.