Figure 10

A snapshot for visualizing T-cell antigenicity of the N-terminal LMP2A. Data from numerous prediction methods were integrated and visualized in form of an HTML table using a Perl framework. Rows contain aligned EBV sequences; colors indicate degree of antigenicity for a particular allele. The snapshot was selected for three spots of potential HLA-B3501 antigenicity. Bars below the alignments indicate (in this order) allele, start position of the ligand, as well as minimum and maximum IC50 in nM of nanomer peptides. Red indicates high affinity ligands (IC50 in nM around 1), blue indicates low affinity ligands (IC50 in nM around 500).