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Table 1 IMGT-ONTOLOGY concepts, IMGT Scientific chart rules and examples of IMGT expertised data concepts.

From: IMGT, the international ImMunoGeneTics information system®: a standardized approach for immunogenetics and immunoinformatics

IMGT-ONTOLOGY main concepts 5 IMGT Scientific chart rules [2] Examples of IMGT expertised data concepts [2]
IDENTIFICATION Standardized keywords [5] Species, molecule type, receptor type, chain type, gene type, structure, functionality, specificity
CLASSIFICATION Reference sequences
Standardized IG and TR gene nomenclature (group, subgroup, gene, allele) [5]
Nomenclature of the human IG and TR genes (entry in 1999 in GDB, HGNC [27] and LocusLink at NCBI) [3, 4]
Alignment of alleles [3, 4]
Nomenclature of the IG and TR genes of all vertebrate species
DESCRIPTION Standardized labels and annotations [5] Core (V-, D-, J-, C-REGION) Prototypes [5]
Labels for sequences
Labels for 2D and 3D structures
NUMEROTATION IMGT unique numbering [14-18] for: V- and V-LIKE-DOMAINs [16]
C- and C-LIKE-DOMAINs [17]
G- and G-LIKE-DOMAINs [18]
Protein displays
IMGT Colliers de Perles [19]
FR-IMGT and CDR-IMGT delimitations [16]
Structural loops and beta strands delimitations [16, 17]
ORIENTATION Orientation of genomic instances relative to each other Chromosome orientation
Locus orientation
Gene orientation
DNA strand orientation
OBTENTION Standardized origin
Standardized methodology [2]