Figure 1
Q-Q plot showing distribution of LDA scores for the HLA-A*0201 community data set. The horizontal axis has been scaled according to normal probabilities, so that points from a normally distributed variable would fall along a straight line (shown in blue). Scores lying above a threshold indicated by a horizontal line would be classified as epitopes. A level exceeding 99% of a normal distribution defines a nominal specificity of 0.99, whereas an actual specificity of 0.99 requires a threshold meeting the actual distribution of points at the 0.99 vertical line. The realized sensitivity of 0.32 for a specificity of 0.99 is indicated as the proportion of epitopes whose scores lie above the threshold of 0.95.