Table 2 Values of three most important indexes (properties) of amino acids determining the peptide-MHC binding Reproduced from [43]1, [11]2 and [44]3
From: Amino acid biophysical properties in the statistical prediction of peptide-MHC class I binding
1L | Name | Volume1 | Hydrophobicity2 | Isoelectric3 |
|---|---|---|---|---|
A | alanine | 88.6 | 1.8 | 6.00 |
C | cysteine | 108.5 | 2.5 | 5.05 |
D | aspartate | 111.1 | -3.5 | 2.77 |
E | glutamate | 138.4 | -3.5 | 3.22 |
F | phenylalanine | 189.9 | 2.8 | 5.48 |
G | glycine | 60.1 | -0.4 | 5.97 |
H | histidine | 153.2 | -3.2 | 7.47 |
I | isoleucine | 166.7 | 3.8 | 5.94 |
K | lysine | 168.6 | -3.9 | 9.59 |
L | leucine | 166.7 | 3.8 | 5.98 |
M | methionine | 162.9 | 1.9 | 5.74 |
N | asparagine | 114.1 | -3.5 | 5.41 |
P | proline | 112.7 | -1.6 | 6.30 |
Q | glutamine | 143.8 | -3.5 | 5.65 |
R | arginine | 173.4 | -4.5 | 11.15 |
S | serine | 89.0 | -0.8 | 5.68 |
T | threonine | 116.1 | -0.7 | 5.64 |
V | valine | 140.0 | 4.2 | 5.96 |
W | tryptophan | 227.8 | -0.9 | 5.89 |
Y | tyrosine | 193.6 | -1.3 | 5.66 |