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Table 3 Major cancer vaccine technologies.

From: Data mining of cancer vaccine trials: a bird's-eye view

Vaccine antigen status

Vaccine technology

Defined antigen

Dendritic cell (peptide)

 

Dendritic cell (protein)

 

Dendritic cell (specific RNA)

 

Dendritic cell (virus)

 

Viral vector (antigen)

 

Viral vector (other)

 

Naked DNA

 

Protein

 

Peptides

 

Anti-idiotype

 

Antigen-specific adjuvant

 

Other

Undefined antigen

Dendritic cells (tumor cell pulsed)

 

Dendritic cells (lysate pulsed)

 

Dendritic cells (allo-lysate pulsed)

 

Allogeneic Dendritic cells (lysate pulsed)

 

Dendritic cells (antigen)

 

Dendritic cells (non-specific DNA)

 

Dendritic cells (non-specific RNA)

 

Dendritic cells (idiotype)

 

Oncolytic virus

 

Autologous (tumor lysate)

 

Allogeneic (tumor lysate)

 

Autologous (tumor cell)

 

Allogeneic (tumor cell)

 

Autologous (T cell)

 

Autologous (lymphocytes)

 

Autologous (PBMC)

 

Immunomodulators

 

Immune activators

 

Other non-cancer vaccines

 

Other

  1. More details about technological platforms for cancer vaccines can be found in [20].