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Figure 1 | Immunome Research

Figure 1

From: Stacking and energetic contribution of aromatic islands at the binding interface of antibody proteins

Figure 1

Flatten view of a binding interface at an antibody (PDB code 1c08). VLTyr50, VLTrp94, VLTyr96, VHTyr33, VHTyr50, VHTyr53, VHTyr58, VHTrp98 (IMGT numbering: V-Kappa Tyr56, V-Kappa Trp114, V-Kappa Tyr116, VH Tyr38, VH Tyr55, VH Tyr58, VH Tyr66, VH Trp107) cluster together to form a spatial “Aromatic Island” (abbreviated to “AI”) at the HyHEL-10 antibody interfaces, which is highlighted with white line (Tyr, colored in dark yellow; Trp, colored in orange). Figure 1 is generated by software JMiV.

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