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Figure 4 | Immunome Research

Figure 4

From: Human immunome, bioinformatic analyses using HLA supermotifs and the parasite genome, binding assays, studies of human T cell responses, and immunization of HLA-A*1101 transgenic mice including novel adjuvants provide a foundation for HLA-A03 restricted CD8+T cell epitope based, adjuvanted vaccine protective against Toxoplasma gondii

Figure 4

HLA-A*1101 transgenic mice immunized with peptide pool and adjuvants. Mice were immunized with PBS, peptide pool, peptide pool with PADRE, peptide pool with PADRE in GLA-SE, peptide pool with PADRE and Pam2Cys in GLA-SE. Splenic T cells were isolated 10-14 days post-immunization and exposed to each peptide in an ex vivo IFN-γ ELISpot assay.

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Immunome Research

ISSN: 1745-7580