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Volume 6 Supplement 2

Computational Vaccinology: State-of-the-art Assessments

  1. Immunoinformatics is an emergent branch of informatics science that long ago pullulated from the tree of knowledge that is bioinformatics. It is a discipline which applies informatic techniques to problems of ...

    Authors: Darren R Flower, Isabel K Macdonald, Kamna Ramakrishnan, Matthew N Davies and Irini A Doytchinova
    Citation: Immunome Research 2010 6(Suppl 2):S1
  2. Identification of epitopes that invoke strong responses from B-cells is one of the key steps in designing effective vaccines against pathogens. Because experimental determination of epitopes is expensive in te...

    Authors: Yasser EL-Manzalawy and Vasant Honavar
    Citation: Immunome Research 2010 6(Suppl 2):S2
  3. Atomistic Molecular Dynamics provides powerful and flexible tools for the prediction and analysis of molecular and macromolecular systems. Specifically, it provides a means by which we can measure theoreticall...

    Authors: Darren R Flower, Kanchan Phadwal, Isabel K Macdonald, Peter V Coveney, Matthew N Davies and Shunzhou Wan
    Citation: Immunome Research 2010 6(Suppl 2):S4
  4. Viruses are fast evolving pathogens that continuously adapt to the highly variable environments they live and reproduce in. Strategies devoted to inhibit virus replication and to control their spread among hos...

    Authors: Samuel Ojosnegros and Niko Beerenwinkel
    Citation: Immunome Research 2010 6(Suppl 2):S5
  5. To properly characterize protective polyclonal antibody responses, it is necessary to examine epitope specificity. Most antibody epitopes are conformational in nature and, thus, cannot be identified using synt...

    Authors: Galina F Denisova, Dimitri A Denisov and Jonathan L Bramson
    Citation: Immunome Research 2010 6(Suppl 2):S6
  6. The last years have seen a renaissance of the vaccine area, driven by clinical needs in infectious diseases but also chronic diseases such as cancer and autoimmune disorders. Equally important are technologica...

    Authors: Johannes Söllner, Andreas Heinzel, Georg Summer, Raul Fechete, Laszlo Stipkovits, Susan Szathmary and Bernd Mayer
    Citation: Immunome Research 2010 6(Suppl 2):S7